The winners of Saturday's games will advance to the Sweet 16 the following weekend.
Below are the matchups, game times (all times Eastern) and television information (network, announcer teams).
MORE: Must-see photos | Interactive bracket | Tournament video | Linemakers’ betting info
Saturday, March 22
(All times ET)
At Orlando
No. 1 Florida 61, No. 9 Pittsburgh 45
No. 4 Louisville 66, No. 5 Saint Louis 51
At Milwaukee
No. 2 Michigan 79, No. 7 Texas 65
No. 2 Wisconsin 85, No. 7 Oregon 77
At Spokane, Wash.
No. 4 San Diego State 63, No. 12 North Dakota State 44
No. 4 Michigan State 80, No. 12 Harvard 73
At Buffalo, N.Y.
No. 11 Dayton 55, No. 3 Syracuse 53
No. 7 Connecticut 77, No. 2 Villanova 65
Sunday, March 23
At St. Louis
No. 10 Stanford 60, No. 2 Kansas 57
No. 8 Kentucky 78, No. 1 Wichita State 76
At San Antonio
No. 3 Iowa State 85, No. 6 North Carolina 83
No. 6 Baylor 85, No. 3 Creighton 55
At Raleigh, N.C.
No. 11 Tennessee 83, No. 14 Mercer 63
No. 1 Virginia 78, No. 8 Memphis 60
San Diego
No. 4 UCLA 77, No. 12 Stephen F. Austin 60
No. 1 Arizona 84, No. 8 Gonzaga 61
