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Alzheimer’s is not a single disease, lead study author Bin Zhang, PhD, director of the center for transformative disease modeling and professor of genetics and genomic sciences at Icahn School of Medicine at Mount Sinai, tells Verywell. He explains that while Alzheimer’s mainly has a genetic component, there are also different types of disease. Looking at multiple subtypes of a disease isn’t new. Zhang says cancer researchers have spent decades looking at cancer in subtypes....

However, a wide range of promising new MS treatments are being studied, including stem cell therapies, drugs that interfere with specific immune system actions, and even dietary nutrients. This article reviews the latest experimental treatments being developed for MS as well as recently approved therapies. Experimental Therapies for MS There are a number of experimental therapies being explored for MS treatment. Masitinib Masitinib is a tyrosine kinase inhibitor that targets overly active immune cells known to play a role in progressive MS....

The database, which tracks diagnoses, hospitalizations and related fatalities across all 50 states connected to COVID-19, showed an average of 53,772 people tested positive for the respiratory syndrome each day during the week preceding Sunday, August 9. The figure represented an 18 percent decrease from average daily cases diagnosed across the country two weeks earlier, when infection rates surged to double those seen in April, at the outbreak’s initial peak....

Video footage uploaded to Twitter by eyewitness Dakota Randall appeared to show the driver with his head pointed fully downwards. A second passenger who was in the vehicle also seemed to have nodded off. The incident was filmed at about 3 p.m. in Newton, close to Exit 17. “Some guy literally asleep at the wheel on the Mass Pike (great place for it). Teslas are sick, I guess?” Randall tweeted yesterday in a post now ’liked’ more than 1,400 times....

The cost of the voyage raised eyebrows, as the edge-of-the-solar-system breakthrough cost $720 million, but the cost of the mission is still less than a number of sporting arenas across the world, including the future home of the Vikings. The newly dubbed U.S. Bank Stadium will cost an estimated $1.1 billion to be built, and could cost even more after a recent fire halted construction. MORE: Sports’ best small stadiums | NFL stadiums: Love ’em or leave ’em?...

Milivie GmbH, the brainchild of artistic engineer Jonathan Engler, has reimagined the Beetle, which ceased production in 2003, as the Milivie 1. The German limited liability company said in a statement obtained by Zenger: “The Milivie 1 is a unique celebration of the world’s most loved vehicle. “The intensely detailed vehicle delivers a fusion of everything the analogue driver desires blended with effortless integration of cutting-edge technology.” Engineers start with a basic original Beetle and take thousands of man-hours to craft it into the new version....

Yet 2021 is here and nothing much seems to have changed: the rate of coronavirus infection is higher than ever and vaccinations against COVID-19 are rolling out slower than anticipated. It’s normal to mourn the plans you’ve had to cancel over the past year or the goals you’ve had to put aside for now. We spoke to some experts on how to cope with these feelings of disappointment in the new year....

The Times Union reported on Wednesday that James’ office issued a subpoena to the state’s Joint Commission on Public Ethics (JCOPE) for its records green-lighting the former governor’s application to receive outside income from the memoir on his administration’s early response to the pandemic. The watchdog’s approval has been criticized for being internally authorized by staffers as opposed to being authorized by a full panel vote, which means the 14 commissioners never voted on the matter....

The breakfast routine is different these days. Aaron is still sleeping when his dad leaves the house for the long commute to work from New Jersey. And it’s dark when dad gets home. They are suburbanites now, the Rosens. A big house, good schools, safe streets. It’s a nice life. But it’s no place like home. The Rosens are part of the New York City diaspora of terror, people who left Manhattan after September 11, whether driven by fear, or despair, or simply because they needed a new start....

The winning numbers on Wednesday were: 01, 05, 06, 07, 16, 48 and the bonus number 25. According to the New York Lotto website, there were no winners of the $9.5 million first prize, nor the $68,670 second prize. 11 players did take home the third prize cash payout of $1,032, however. A further 1,008 players each won $12 and 17,866 players won $1. The New York Lotto jackpot now increases by $300,000 to $9....

In a Monday speech to the China Business Summit in Auckland, Ardern said New Zealand has raised “grave” concerns with China on human rights issues, including the situation of Uyghurs in the Xinjiang region and residents in Hong Kong. “It will not have escaped the attention of anyone here that as China’s role in the world grows and changes, the differences between our systems—and the interests and values that shape those systems—are becoming harder to reconcile,” Ardern told the audience....

After visiting baby Eevee, Wendell’s sister started developing coronavirus symptoms. When the baby appeared out of sorts, Wendell went to get her infant tested for COVID-19—and was heartbroken to find out she had tested positive. “I’ve never had another baby to experience any other illness with, so when you find out it’s COVID, it’s just heartbreaking,” said Wendell to ABC 15 Arizona, “I started panicking because I didn’t know what was going to happen”....

The 21-year-old midfielder joined the newly-promoted Premier League side from Borussia Dortmund on an initial loan deal, which includes an obligation to buy him after 20 appearances. Newcastle 21/10 to beat Swansea The Spain Under 21 international has played in all three of Newcastle’s league games this season and has made an immediate impression on fans. And Merino is happy to hear the amusing chant the Magpies fans have already made about him....

The winger has been out of action since straining a muscle while attempting a shot in a league fixture with Bournemouth last month. With the injury initially not thought to be serious, Atsu headed for international duty after the game but a relapse while training with Ghana sent him to the sidelines. “[Jamal] Lascelles and Atsu, they are available," Benitez said on Friday. “[Paul] Dummett will play with the Under-23s today to improve his match fitness....

The Algeria international who joined the Magpies on loan from Leicester was unable to make his much-anticipated debut in their 1-0 famous victory over Manchester United. The former Sporting CP player suffered a thigh muscle strain in training on January 30 which he has been struggling with since his arrival at the St James’ Park. Though he trained with the club for the first time on Wednesday, the gaffer has stated why the forward failed to make his bow....

The Magpies are looking to continue their resurgence under Rafael Benitez after claiming the Championship title last season. The latest summer transfer rumours They face a tough start to the campaign, however, against a Spurs side that finished second to champions Chelsea in 2016-17 and will have its eye on the title this time around. TV CHANNEL & LIVE STREAM In the UK, the match will be available to watch live on television on Sky Sports Premier League and by stream via Sky Go....

Shannen Doherty: I’m good, thank you. I’m unpacking from New York. I can’t stand unpacking. No! I’m a normal person. My housekeeper has better things to do. I help relationships come to an end or sometimes help them go to the next level. It can be boyfriend or girlfriend, or if you want to quit your job. No, and if that’s the way you’re going with this then I’d rather not even do the interview....

Applicants must have experience reporting and writing for their college newspapers, in previous internships or at other publications. We ask applicants to submit: A one-page letter stating their qualifications and aspirations A detailed résumé Five samples of published articles*, including name and date of publication. Essays for classes are not acceptable. Name and phone number of two references *Clips should demonstrate exclusive or enterprise reporting which, ideally, had an impact....

The challenge you will face in the next few months is stark. Do you want to remain vague? You might win—but you might find that, in winning, you have a “victory of personality” with no real policy consequences. Or do you want to provide specifics? If so, your victory could be a clarion call from the American people to Congress to join you in achieving your goals. I participated in two successful “change” campaigns: the Reagan revolution of 1980 and the “Contract With America” in 1994....